A partnership between the Universities of Brighton and Sussex with the NHS

 

infection and inflammation

Name: Dr Gail Davey

Academic position: Senior Clinical Research Fellow

Contact details:

Brighton and Sussex Medical School
University of Sussex
Falmer
Brighton BN1 9PX
UK

Or

PO Box 26905/1000, Addis Ababa, Ethiopia

E-mail:

 

Biography:

• MRCGP (London)1999  
• MD (Cambridge University)1998
• MSc Epidemiology (University of London)1997  
• MRCP (London)1993 
• MA (Cambridge University)1993
• MBBChir (Cambridge University)1990

 

Background:

I am a medical epidemiologist with a primary care qualification specializing in non-communicable diseases in a low-income country setting. Over the last seven years,I have gained extensive experience of postgraduate teaching and research in Ethiopia, and have developed a wide network of contacts within Ethiopian Higher Education and research institutions and acted as a focal personfor many international collaborations. My place of employment at Addis Ababa University has given me a unique vantage point from which to identify and develop the most outstanding Ethiopian postgraduate students.

Teaching role:

Teaching Qualifications & Courses

2001 Member, UK Insitute of Learning & Teaching

1999 Presentation Skills, St Greorge's Hospital Medical School

1999 Teaching Skills for Clinical Teachers, SGHMS

 

Undergraduate teaching                                                                                       

2003-date        Research elective supervision: 4 British & 2 Dutch medical students

2001-date        Research Methods and Presentation Skills to 6th Year medical students

2002-2006       Field supervision of 6th Year students on Rural Community Health placement

 

Postgraduate teaching

36 MPH & MSc research theses, Addis Ababa University

2005-date        MPH Advanced Epidemiology Track

2002-date        MPH Research Methods course

2001-date        MPH Basic Epidemiology

2001-date        MPH Presentation Skills courses

 

MSc Microbiology & Parasitology, Addis Ababa University

2005-2008 Basic Epidemiology & Research Methods

 

MPH, University of Nottingham

2006-2008     Global Perspectives on Public Health (1/3 of module)

 

Clinical Speciality Training, Addis Ababa University

2007-2008      Research Methods for Dermatology Residents

2006                Clinical Epidemiology for Neurology Residents

MPH/MSc Research Supervision

2001-2008       Advisor for 32 MPH and MSc Research Theses

 

Workshop: Molecular Medicine & Genomics in Africa, Khartoum, 2008

‘Exploring genetic influences in podoconiosis – a tropical model of gene-environment interaction’ to MSc & PhD students from Africa and Middle East.

 

PhD in Public Health, Addis Ababa University

2005-date      Special Topics in Epidemiology (Year 1, Semester 2)

 

PhD Research Supervision

2007-date       Supervision of Fasil Tekola, registered for PhD at Brighton & Sussex Medical School.

2007-date       Supervision of Dereje Habte, registered for PhD at AAU

2007-date       Supervision of Wubegzier Mekonnen, registered for PhD at AAU

2008                Supervision of Alemayehu Amberbir, registered for PhD at University of Nottingham

 

Course Coordination                                                                        

2006-date        Course Coordinator, Basic Epidemiology (MPH)

2006-date        Couse Coordinator, Special Topics in Epidemiology (PhD)

2007-date        Course Coordinator, Advanced Epidemiology Block 1 (MPH)

Program Coordination

2006-date        PhD Program Coordinator (one of two coordinators, responsible for recruitment and selection of students, coordination of courses and instructors within program, pastoral care of students, organization of external examiners and final defence)

Curriculum Development

2008                Lead, development of joint MPH/Veterinary Public Health curriculum

2004                Committee, development of MPH Advanced Epidemiology track

1999                Faculty team, development of Accelerated Graduate Entry Program curriculum at St George’s Hospital Medical School

Current research:

Since 2005, my main area of research has been podoconiosis (endemic non-filarial elephantiasis). I have developed, secured funding for, and led, a multidisciplinary program of research into podoconiosis which covers aetiology (genetic and biochemical) and consequences (economic and social) of disease. Alongside this research, I have assisted a local NGO in developing a primary care strategy to provide prevention, treatment and rehabilitation to an area of 1.5m residents.  Parallel with my clinical and research work in this area I have also raised the local and international profile of the disease using a range of advocacy tools.

 

Current/recent laboratory funding:

2010-2013       Wellcome Trust. Adoption of rapid ethical appraisal as a practical method of assessing ethical issues relating to biomedical research projects in Ethiopia. (PhD Studentship for Dr Adamu Addissie). £96,939.

2009-2011       NIH Social & Behavioural Research Branch. Using Behavioural Research to Optimize Shoe Use and Enhance Prevention of Podoconiosis. $45,625.

2010-2011       MRC Biomedical Research Unit (Respiratory Medicine).  Immunological Measurements in an Ethiopian Birth Cohort. £60,000.

2009-2010       Association of Physicians of Great Britain and Northern Ireland. Building links in Histopathology and Geology between Ethiopia and the UK through elucidation of the role of ultrafine particles in pathogenesis of podoconiosis. £9823.

2008-2011       Asthma UK. Effects of intestinal parasite infection on the incidence of wheeze and allergic sensitization in an Ethiopian birth cohort.  £108009. Co-applicant; PI: Prof John Britton.

2007-2009       Wellcome Trust. The genetic basis of podoconiosis - a model for gene-environment interaction? £280,187. Co-PI with Dr Melanie Newport.

2007-2008       Association of Physicians of Great Britain and Northern Ireland.  Measurement of oxidative stress in podoconiosis. £9,980. PI.

2007-2008       Asthma UK. Randomised controlled trial of the effects of paracetamol withdrawal on bronchial reactivity and asthma symptoms. £30,505. Co-Applicant.*

2007                Nottingham University ICR Pump-priming grant. Measurement of expired nitric oxide in a randomised controlled trial of paracetamol withdrawal in patients with asthma. £5,000. Co-PI with Dr Andrew Fogarty.

2004-2006       Association of Physicians of Great Britain and Northern Ireland.  Validation of the IUATLD Bronchial Symptoms Questionnaire to enhance asthma diagnosis and treatment in and Ethiopian population. £9,993. PI.

2003-2005       Association of Physicians of Great Britain and Northern Ireland.  Establishing the genetic epidemiology of and the economic losses due to podoconiosis (endemic non-filarial elephantiasis) in Ethiopia. £9,967. PI.

2002-2004 Asthma UK. The relation between atopy, asthma and parasite infection in urban and rural populations in Butajira, Ethiopia. £44,115 Co-applicant; PI: Prof John Britton.

2002                British Embassy Small Grants Scheme. Presentation Skills for Masters in Public Health students. 1,672 Birr.

*Following serious injury to a co-applicant, this grant has been returned to the funding body.

 

Key/recent publications:

Original Peer-reviewed Scientific Papers:

• Prevalence and risk factors of wheeze and eczema in one year old children: the Butajira Birth Cohort, Ethiopia. Belyhun Y, Medhin G, Amberbir A, Erko B, Hanlon C, Alem A, Venn A, Britton J, Davey G. Clin Exp Allergy (accepted).
• Prevalence and risk factors for soil transmitted helminth infection in mothers and their infants in Butajira, Ethiopia: A population based study. Belyhun Y, Medhin G, Amberbir A, Erko B, Hanlon C, Alem A, Venn A, Britton J, Davey G. BMC Public Health (accepted).
• The role of transforming growth factor β1 and oxidative stress in podoconiosis pathogenesis. Addisu S, El-Metwally TH, Davey G, Worku Y, Titheradge M. BJD (in press).
• Health Professionals' Attitudes and Misconceptions regarding Podoconiosis: Potential Impact on Integration of Care in southern Ethiopia. Yakob B, Kebede D, Davey G. Trans Roy Soc Trop Med Hyg 2010;104:42-47.
• Impact of social stigma on the process of obtaining informed consent for genetic research on podoconiosis: a qualitative study. Tekola F, Bull S, Farsides B, Newport M, Rotimi C, Adeyemo A, Davey G. BMC Medical Ethics 2009;10:13.
• Tailoring Consent to Context: Designing an Appropriate Consent Process for a Biomedical Study in a Low Income Setting. Tekola F, Bull S, Farsides B, Newport M, Rotimi C, Adeyemo A, Davey G. PLoS NTD 2009;3(7):e482.
• Community-based care of a neglected tropical disease: The Mossy Foot Treatment and Prevention Association. Davey G, Burridge E. PLoS NTD 2009;3(5):e424.
• Implications of the HIV testing protocol for refusal bias in seroprevalence surveys.  Reniers G, Araya T, Davey G, Berhane Y, Sanders E. BMC Public Health 2009;9:163.
• Repeatability and validity of IUATLD respiratory questionnaire responses as a measure of asthma in an Ethiopian population. Denboba W, Venn A, Britton J, Davey G. East Afr Med J 2009;85:582-8.
• How do people protect themselves from dual risk of unintended pregnancy and HIV/AIDS?  Teklu T, Davey G. Eth J Health Dev 2009;22:226-23.
• Steep declines in population-level AIDS mortality following the introduction of antiretroviral therapy in Addis Ababa, Ethiopia. Reniers G, Araya T, Davey G, Berhane Y, Coutinho R, Sanders E. AIDS 2009;23:511-518.
• Assessment of respiratory function in patients with podoconiosis. Morrison C, Davey G. Trans Roy Soc Trop Med Hyg 2009;103:315-317.
• and citations completed on these 3:
• The Economic Impact of HIV/AIDS Morbidity and Mortality on Households in Addis Ababa, Ethiopia. Tekola F, Reniers G, HaileMariam D, Araya T, Davey G. AIDS Care 2008;20:995-1001.
• Development and testing of a de novo staging system for podoconiosis. Tekola F, Ayele Z, HaileMariam D, Fuller C, Davey G. Trop Med Int Health 2008;13:1277-83.
• Validation of the Dermatology Life Quality Index among patients with podoconiosis in southern Ethiopia. Henok L, Davey G. Br J Derm 2008;159:903-6.
• Development and testing of a de novo staging system for podoconiosis. Tekola F, Ayele Z, HaileMariam D, Fuller C, Davey G. Trop Med Int Health (in press).
• Validation of the Dermatology Life Quality Index among patients with podoconiosis in southern Ethiopia. Henok L, Davey G. Br J Derm (in press).
• The Economic Impact of HIV/AIDS Morbidity and Mortality on Households in Addis Ababa, Ethiopia. Tekola F, Reniers G, HaileMariam D, Araya T, Davey G. AIDS Care (in press).
• High levels of misconceptions and stigma in a community highly endemic for podoconiosis in southern Ethiopia. Yakob B, Deribe K, Davey G. Trans Roy Soc Trop Med Hyg. 2008 (102):439-444.
• Status Epilepticus: clinical presentation, cause, outcome and predictors of death in 119 Ethiopian patients. Amare A, Zenebe G, Hammack J, Davey G. Epilepsia. Published online: 4-Mar-2008 doi: 10.1111/j.1528-1167.2008.01556.
• Predictive value of clinical assessment of patients with podoconiosis in an endemic community setting (Short Communication). Desta K, Ashine M, Davey G. Trans Roy Soc Trop Med Hyg 2007 (101):621-623.
• Factors predisposing out of school youth to HIV/AIDS related risky sexual behavior in Northwest Ethiopia. Alemu H, HaileMariam D, Belay KA, Davey G. J Health Dev & Nutr 2007;25:344-350.
• Podoconiosis: a tropical model of gene-environment interaction? Davey G, GebreHanna E, Adeyemo A, Rotimi C, Newport M, Desta K. Trans Roy Soc Trop Med Hyg 2007;101:91-96.
• The role of men in contraceptive use and fertility preference in Hossana Town, southern Ethiopia. Tuloro T, Deressa W, Ali A, Davey G. Eth J Health Dev 2006;20:152-159.
• Economic costs of podoconiosis (non-filarial elephantiasis) in Wolaita Zone, Ethiopia. Tekola F, HaileMariam D, Davey G. Trop Med Int Health 2006;11:1136-1144.
• Antiretroviral treatment adherence and its correlates in Addis Ababa, Ethiopia. Tadios Y, Davey G. Eth Med J 2006;44: 237-244.
• Assessment of the utilization of pre-marital HIV testing and its determinants in Addis Ababa, 2003. Habte D, Deyessa N, Davey G. Eth J Health Dev 2006;20:18-23.
• Use and misuse of paracetamol and aspirin in rural Ethiopia: study with qualitative and quantitative components. Duncan P, Aref-Adib G, Venn A, Britton J, Davey G. E Afr Med J 2006;83:31-36.
• Prevalence and predictors of smoking in Butajira town, Ethiopia, 2003. Schoenmaker N, Hermanides J, Davey G. Eth J Health Dev 2006;19:182-187.
• Use of acetaminophen and the risk of self-reported allergic symptoms and skin sensitization in Butajira, Ethiopia. Davey G, Berhane Y, Duncan P, Aref-Adib G, Britton J, Venn A. J Allergy Clin Immunol 2005;116:863-8.
• Wheeze, allergic sensitization and geohelminth infection in Butajira, Ethiopia. Davey G, Venn A, Belete H, Berhane Y, Britton J. Clin Exp Allergy. 2005;35:301-307.
• Prevalence of podoconiosis (non-filarial elephantiasis) in Wolaitta, Southern Ethiopia. Destas K, Ashine M, Davey G. Trop Doc 2003;32:217-220.
• Overall HIV-1 prevalence in pregnant women from Afar region over-estimates HIV-1 in the general population. Assefa T, Davey G, Dukers N, et al.  Eth Med J 2003;41: 43-49.
• Association between migraine and asthma: nested case-control study in the General Practice Research Database (GPRD).  Davey G, Sedgwick P,  Maier W, Visick G, Strachan D, Anderson R.  Br J GP 2002;52:723-727.
• The Great Ethiopian Run: Incidence of injury; a descriptive study (Short Report).  Davey G, Tilahun S.  Eth J Health Dev 2002;16:233-234.
• Familial aggregation of central adiposity among Southern Indians. Davey G, Ramachandran A, Snehalatha C, Hitman GA, McKeigue PM. Int J Obesity 2000:24;1523-27.
•  Effects of exercise on insulin resistance in South Asians and Europeans. Davey G, Roberts JD, Patel S, Pierpoint T, Godsland IF, Davies B, McKeigue PM. J Ex Physiol Online 2000:3(2) 6-11.
• Associations between insulin levels and cardiovascular disease are confounded by comorbidity. McKeigue P, Davey G.  Diab Care 1995;18:1-5.

Reviews, Editorials and Comments:

• Recent advances in podoconiosis. (Review). Davey G. Ann Trop Med Parasitol 2009;103:5:1-6.
• Die Podokoniose als nicht-filariöse, geochemische bedingte Elephantiasis - eine vergessene tropische Erkrankung? (Review) Nennoff PG, Muylowa K, Davey G. JDDG 2010:8:7-14.
• Podoconiosis: let Ethiopia lead the way (Editorial). Davey G. Eth J Health Dev (in press).
• Podoconiosis: non-infectious geochemical elephantiasis. Davey G, Tekola F, Newport M. Trans Roy Soc Trop Med Hyg 2007 (101):1175-1180
• Podoconiosis: the most neglected tropical disease? (Comment) Davey G, Newport M. Lancet 2007;369:888-889.
• Must aid hinder attempts to reach the Millennium Development Goals? (Comment) Davey G, Fekade D, Parry EHO. Lancet.2006;367:629-630.
• Paracetamol, antioxidants and asthma (Editorial).  Fogarty A, Davey G.  Clin Exp Allergy. 2005;35:700-702.
• Adapting international protocols to local settings (Editorial). Davey G. Trop Doc 2001;31:65.
• Insulin infusion in diabetic patients with acute myocardial infarction (Review). Davey G, McKeigue PM BMJ 1996: 313:639-640.

Book Chapters:

• Podoconiosis. Davey G. In 'The Oxford Textbook of Medicine'. Eds. Warrell, Cox, Firth. 5th ed, 2010, in press.
• Podoconiosis (non-filarial elephantiasis). Davey G. In ‘The Ecology of Health and Disease in Ethiopia’. Eds. Kloos, Yemane & HaileMariam. 2nd ed, 2005.

Literature & Medicine:

• Exodus. Davey G. Joint winner, Lancet Short Story Prize, 2007.
• Still life and the rounding of consciousness. Davey G. Lancet 1998:352:1544-47.
  

 

Other information:

Research Planned:

• Fine mapping of podoconiosis susceptibility gene (with Prof Melanie Newport, Brighton & Sussex Medical School, Prof Charles Rotimi and Dr Adebowale Adeyemo, Human Genome Lab, National Institutes of Health, US)
•  Replication of genetic findings in a Cameroonian population (with Dr Samuel Wanji, University of Buea; Prof Melanie Newport, Brighton & Sussex Medical School; and Prof Charles Rotimi, Human Genome Lab, National Institutes of Health, US).
• Characterization of grain size, bulk composition, silica content and toxicity of volcanic soils of podoconiosis-endemic areas (with Dr Peter Baxter, University of Cambridge; Dr Javier Cuadros, Natural History Museum, London; & Dr Mohammed Umer, Addis Ababa University).
• Measurement of haematological profile of patients with podoconiosis (with Dr Aster Tsegaye, Kassu Desta & Bineyam Taye, School of Medical & Lab Sciences, Addis Ababa University).
• RCT to identify most effective means of encouraging use of footwear among high risk children (with Dr Getnet Tadele, School of Social Sciences, Dr Mulugeta Betre, School of Public Health, Addis Ababa University; Dr Colleen McBride & Dr Dirk De Heer, Human Genome Lab, Social & Behavioural Research Branch, National Institutes of Health).

 

Membership of Learned Socities:

2006-date        Fellow, Royal Society of Tropical Medicine & Hygiene

2004-date        Member, African Society for Human Genetics

2002-date        Member, Ethiopian Public Health Association

2002-date        Member, Ethiopian Medical Association

 

Research Presentations (national and international):

2009   Summer Institute in Public Health Genomics, Seattle - invited speaker

2009   14th International Clay Conference, Italy - invited speaker

2009    Wellcome Trust Frontiers Meeting, Cameroon-invited speaker

2008    RSTM&H/Norwegian Tropical Disease Society, Oslo - invited speaker

2008    International Association of Research Managers, Liverpool - invited speaker

2007   African Society for Human Genetics, Cairo - research talk

2007   RSTM&H Centenary Conference, London - research talk

2007   Tropical & International Dermatology, London - invited speaker

2006   Armauer Hansen Scientific Advisory Board, Addis Ababa - invited speaker

2006   African Society for Human Genetics, Addis Ababa - research talk

2005   Ethiopian Medical Association, Addis Ababa - invited speaker

2005   American Thoracic Society, Orlando - research talk

2004   Ethiopian Medical Association, Addis Ababa - research talks

2003   Ethiopian Public Health Association, Addis Ababa - research talks

2003    Ethiopian Medical Association, Addis Ababa - research talks

2002    Ethiopian Medical Association, Addis Ababa - research poster

2000   Deadly Triad Conference, Leicester - research talk