infection and inflammation

Name: Dr Gail Davey

Academic position: Senior Clinical Research Fellow

Research:

I am a medical epidemiologist with a primary care qualification specializing in non-communicable diseases in a low-income country setting. Over the last seven years, I have gained extensive experience of postgraduate teaching and research in Ethiopia, and have developed a wide network of contacts within Ethiopian Higher Education and research institutions and acted as a focal person for many international collaborations. My place of employment at Addis Ababa University has given me a unique vantage point from which to identify and develop the most outstanding Ethiopian postgraduate students.

Contact details:

Brighton and Sussex Medical School
University of Sussex
Falmer
Brighton BN1 9PX
UK

PO Box 26905/1000, Addis Ababa, Ethiopia

E-mail:

Biography:

MRCGP (London)1999
MD (Cambridge University)1998
MSc Epidemiology (University of London)1997
MRCP (London)1993
MA (Cambridge University)1993
MBBChir (Cambridge University)1990

Teaching role:

Teaching Qualifications & Courses

2001 Member, UK Insitute of Learning & Teaching

1999 Presentation Skills, St Greorge's Hospital Medical School

1999 Teaching Skills for Clinical Teachers, SGHMS

Undergraduate teaching

2003-date Research elective supervision: 4 British & 2 Dutch medical students

2001-date Research Methods and Presentation Skills to 6th Year medical students

2002-2006 Field supervision of 6th Year students on Rural Community Health placement

Postgraduate teaching

MPH, Addis Ababa University

2005-date MPH Advanced Epidemiology Track

2002-date MPH Research Methods course

2001-date MPH Basic Epidemiology

2001-date MPH Presentation Skills courses

MSc Microbiology & Parasitology, Addis Ababa University

2005-2008 Basic Epidemiology & Research Methods

MPH, University of Nottingham

2006-2008 Global Perspectives on Public Health (1/3 of module)

Clinical Speciality Training, Addis Ababa University

2007-2008 Research Methods for Dermatology Residents

2006 Clinical Epidemiology for Neurology Residents

MPH/MSc Research Supervision

2001-2008 Advisor for 32 MPH and MSc Research Theses

Workshop: Molecular Medicine & Genomics in Africa, Khartoum, 2008

‘Exploring genetic influences in podoconiosis – a tropical model of gene-environment interaction’ to MSc & PhD students from Africa and Middle East.

PhD in Public Health, Addis Ababa University

2005-date Special Topics in Epidemiology (Year 1, Semester 2)

PhD Research Supervision

2007-date Supervision of Fasil Tekola, registered for PhD at Brighton & Sussex Medical School.

2007-date Supervision of Dereje Habte, registered for PhD at AAU

2007-date Supervision of Wubegzier Mekonnen, registered for PhD at AAU

2008 Supervision of Alemayehu Amberbir, registered for PhD at University of Nottingham

Course Coordination

2006-date Course Coordinator, Basic Epidemiology (MPH)

2006-date Couse Coordinator, Special Topics in Epidemiology (PhD)

2007-date Course Coordinator, Advanced Epidemiology Block 1 (MPH)

Program Coordination

2006-date PhD Program Coordinator (one of two coordinators, responsible for recruitment and selection of students, coordination of courses and instructors within program, pastoral care of students, organization of external examiners and final defence)

Curriculum Development

2008 Lead, development of joint MPH/Veterinary Public Health curriculum

2004 Committee, development of MPH Advanced Epidemiology track

1999 Faculty team, development of Accelerated Graduate Entry Program curriculum at St George’s Hospital Medical School

Current research:

Since 2005, my main area of research has been podoconiosis (endemic non-filarial elephantiasis). I have developed, secured funding for, and led, a multidisciplinary program of research into podoconiosis which covers aetiology (genetic and biochemical) and consequences (economic and social) of disease. Alongside this research, I have assisted a local NGO in developing a primary care strategy to provide prevention, treatment and rehabilitation to an area of 1.5m residents. Parallel with my clinical and research work in this area I have also raised the local and international profile of the disease using a range of advocacy tools.

Current/recent laboratory funding:

2008-2011 Asthma UK. Effects of intestinal parasite infection on the incidence of wheeze and allergic sensitization in an Ethiopian birth cohort. £108009. Co-applicant; PI: Prof John Britton.

2007-2009 Wellcome Trust. The genetic basis of podoconiosis - a model for gene-environment interaction? £280,187. Co-PI with Dr Melanie Newport.

2007-2008 Association of Physicians of Great Britain and Northern Ireland. Measurement of oxidative stress in podoconiosis. £9,980. PI.

2007-2008 Asthma UK. Randomised controlled trial of the effects of paracetamol withdrawal on bronchial reactivity and asthma symptoms. £30,505. Co-Applicant*

2007 Nottingham University ICR Pump-priming grant. Measurement of expired nitric oxide in a randomised controlled trial of paracetamol withdrawal in patients with asthma. £5,000. Co-PI with Dr Andrew Fogarty

2004-2006 Association of Physicians of Great Britain and Northern Ireland. Validation of the IUATLD Bronchial Symptoms Questionnaire to enhance asthma diagnosis and treatment in and Ethiopian population. £9,993. PI.

2003-2005 Association of Physicians of Great Britain and Northern Ireland. Establishing the genetic epidemiology of and the economic losses due to podoconiosis (endemic non-filarial elephantiasis) in Ethiopia. £9,967. PI.

2002-2004 Asthma UK. The relation between atopy, asthma and parasite infection in urban and rural populations in Butajira, Ethiopia. £44,115 Co-applicant; PI: Prof John Britton.

2002 British Embassy Small Grants Scheme. Presentation Skills for Masters in Public Health students. 1,672 Birr.

*Following serious injury to a co-applicant, this grant has been returned to the funding body.

Key/recent publications:

Original Peer-reviewed Scientific Papers:

Development and testing of a de novo staging system for podoconiosis. Tekola F, Ayele Z, HaileMariam D, Fuller C, Davey G. Trop Med Int Health (in press).
Validation of the Dermatology Life Quality Index among patients with podoconiosis in southern Ethiopia. Henok L, Davey G. Br J Derm (in press).
The Economic Impact of HIV/AIDS Morbidity and Mortality on Households in Addis Ababa, Ethiopia. Tekola F, Reniers G, HaileMariam D, Araya T, Davey G. AIDS Care (in press).
High levels of misconceptions and stigma in a community highly endemic for podoconiosis in southern Ethiopia. Yakob B, Deribe K, Davey G. Trans Roy Soc Trop Med Hyg. 2008 (102):439-444.
Status Epilepticus: clinical presentation, cause, outcome and predictors of death in 119 Ethiopian patients. Amare A, Zenebe G, Hammack J, Davey G. Epilepsia. Published online: 4-Mar-2008 doi: 10.1111/j.1528-1167.2008.01556.
Predictive value of clinical assessment of patients with podoconiosis in an endemic community setting (Short Communication). Desta K, Ashine M, Davey G. Trans Roy Soc Trop Med Hyg 2007 (101):621-623.
Factors predisposing out of school youth to HIV/AIDS related risky sexual behavior in Northwest Ethiopia. Alemu H, HaileMariam D, Belay KA, Davey G. J Health Dev & Nutr 2007;25:344-350.
Podoconiosis: a tropical model of gene-environment interaction? Davey G, GebreHanna E, Adeyemo A, Rotimi C, Newport M, Desta K. Trans Roy Soc Trop Med Hyg 2007;101:91-96.
The role of men in contraceptive use and fertility preference in Hossana Town, southern Ethiopia. Tuloro T, Deressa W, Ali A, Davey G. Eth J Health Dev 2006;20:152-159.
Economic costs of podoconiosis (non-filarial elephantiasis) in Wolaita Zone, Ethiopia. Tekola F, HaileMariam D, Davey G. Trop Med Int Health 2006;11:1136-1144.
Antiretroviral treatment adherence and its correlates in Addis Ababa, Ethiopia. Tadios Y, Davey G. Eth Med J 2006;44: 237-244.
Assessment of the utilization of pre-marital HIV testing and its determinants in Addis Ababa, 2003. Habte D, Deyessa N, Davey G. Eth J Health Dev 2006;20:18-23.
Use and misuse of paracetamol and aspirin in rural Ethiopia: study with qualitative and quantitative components. Duncan P, Aref-Adib G, Venn A, Britton J, Davey G. E Afr Med J 2006;83:31-36.
Prevalence and predictors of smoking in Butajira town, Ethiopia, 2003. Schoenmaker N, Hermanides J, Davey G. Eth J Health Dev 2006;19:182-187.
Use of acetaminophen and the risk of self-reported allergic symptoms and skin sensitization in Butajira, Ethiopia. Davey G, Berhane Y, Duncan P, Aref-Adib G, Britton J, Venn A. J Allergy Clin Immunol 2005;116:863-8.
Wheeze, allergic sensitization and geohelminth infection in Butajira, Ethiopia. Davey G, Venn A, Belete H, Berhane Y, Britton J. Clin Exp Allergy. 2005;35:301-307.
Prevalence of podoconiosis (non-filarial elephantiasis) in Wolaitta, Southern Ethiopia. Destas K, Ashine M, Davey G. Trop Doc 2003;32:217-220.
Overall HIV-1 prevalence in pregnant women from Afar region over-estimates HIV-1 in the general population. Assefa T, Davey G, Dukers N, et al. Eth Med J 2003;41: 43-49.
Association between migraine and asthma: nested case-control study in the General Practice Research Database (GPRD). Davey G, Sedgwick P, Maier W, Visick G, Strachan D, Anderson R. Br J GP 2002;52:723-727.
The Great Ethiopian Run: Incidence of injury; a descriptive study (Short Report). Davey G, Tilahun S. Eth J Health Dev 2002;16:233-234.
Familial aggregation of central adiposity among Southern Indians. Davey G, Ramachandran A, Snehalatha C, Hitman GA, McKeigue PM. Int J Obesity 2000:24;1523-27.
Effects of exercise on insulin resistance in South Asians and Europeans. Davey G, Roberts JD, Patel S, Pierpoint T, Godsland IF, Davies B, McKeigue PM. J Ex Physiol Online 2000:3(2) 6-11.
Associations between insulin levels and cardiovascular disease are confounded by comorbidity. McKeigue P, Davey G. Diab Care 1995;18:1-5.

Reviews, Editorials and Comments:

Podoconiosis: let Ethiopia lead the way (Editorial). Davey G. Eth J Health Dev (in press).
Podoconiosis: non-infectious geochemical elephantiasis. Davey G, Tekola F, Newport M. Trans Roy Soc Trop Med Hyg 2007 (101):1175-1180
Podoconiosis: the most neglected tropical disease? (Comment) Davey G, Newport M. Lancet 2007;369:888-889.
Must aid hinder attempts to reach the Millennium Development Goals? (Comment) Davey G, Fekade D, Parry EHO. Lancet.2006;367:629-630.
Paracetamol, antioxidants and asthma (Editorial). Fogarty A, Davey G. Clin Exp Allergy. 2005;35:700-702.
Adapting international protocols to local settings (Editorial). Davey G. Trop Doc 2001;31:65.
Insulin infusion in diabetic patients with acute myocardial infarction (Review). Davey G, McKeigue PM BMJ 1996: 313:639-640.

Book Chapters:

Podoconiosis. Davey G. In 'The Oxford Textbook of Medicine'. Eds. Warrell, Cox, Firth. 5th ed, 2008.
Podoconiosis (non-filarial elephantiasis). Davey G. In ‘The Ecology of Health and Disease in Ethiopia’. Eds. Kloos, Yemane & HaileMariam. 2nd ed, 2005.

Literature & Medicine:

Exodus. Davey G. Joint winner, Lancet Short Story Prize, 2007.
Still life and the rounding of consciousness. Davey G. Lancet 1998:352:1544-47.

Other information:

Research Planned:

Measurement of particle size and proportion crystalline silica in volcanic soils of podoconiosis-endemic areas (with Dr P Baxter & Prof K Donaldson)
In-vitro studies to assess toxicity of nanoparticles of volcanic soils on macrophages (with Dr P Baxter & Prof K Donaldson)
Mapping of extent of podoconiosis across Ethiopia (with Dr S Hay).
Mapping of extent of podoconiosis across tropical Africa.
Assessment of effectiveness of expansion of Mossy Foot intervention to two new zones in Ethiopia.

Membership of Learned Socities:

2006-date Fellow, Royal Society of Tropical Medicine & Hygiene

2004-date Member, African Society for Human Genetics

2002-date Member, Ethiopian Public Health Association

2002-date Member, Ethiopian Medical Association

Research Presentations (national and international):

2008 RSTM&H/Norwegian Tropical Disease Society, Oslo - invited speaker

2008 International Association of Research Managers, Liverpool - invited speaker

2007 African Society for Human Genetics, Cairo - research talk

2007 RSTM&H Centenary Conference, London - research talk

2007 Tropical & International Dermatology, London - invited speaker

2006 Armauer Hansen Scientific Advisory Board, Addis Ababa - invited speaker

2006 African Society for Human Genetics, Addis Ababa - research talk

2005 Ethiopian Medical Association, Addis Ababa - invited speaker

2005 American Thoracic Society, Orlando - research talk

2004 Ethiopian Medical Association, Addis Ababa - research talks

2003 Ethiopian Public Health Association, Addis Ababa - research talks

2003 Ethiopian Medical Association, Addis Ababa - research talks

2002 Ethiopian Medical Association, Addis Ababa - research poster

2000 Deadly Triad Conference, Leicester - research talk