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BSMS > About BSMS > Contact us > Staff > Dr Marco Bozzali

Dr Marco Bozzali

marco bozzali

Dr Marco Bozzali

Senior Lecturer (Honorary Consultant) in Neurology
T: +44 (0)1273 873509
Location: Room 201, Trafford Centre for Medical Research, University of Sussex, BN1 9RY

PA: Pat Butler

T: +44 (0)1273 876768

Areas of expertise: Multiple sclerosis, Myotonic Dystrophy and Dementia

Research areas: Neurodegeneration; Neuroinflammation; Quantitative neuroimaging


Marco Bozzali obtained his degree in Medicine and Surgery at Università degli Studi di Milano (University of Milan, Italy) in 1997, and completed his Specialist Neurology training in 2003. Between 1998 and 2003, he worked at the Department of Neurology and the Neuroimaging Research Unit at the Research Hospital San Raffaele, in Milan. In 2003, Marco took up the position of Clinical Research fellow at the Wellcome Trust Centre for Neuroimaging and the Institute of Cognitive Neuroscience, University College London (Supervisor Prof Tim Shallice). At the same time worked as Honorary Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, London. In 2006, he moved back to Italy working as Consultant in Neurology at the Department of Clinical and Behavioural Neurology and the Director of the Clinical Science theme of the Neuroimaging Laboratory of Santa Lucia Foundation, IRCCS, Rome. In 2017, he was appointed Senior Lecturer (Honorary Consultant) in Neurology at BSMS. He still maintains the role of PI at the Neuroimaging Laboratory of Santa Lucia Foundation in Rome.


Since the beginning of his career, Marco has worked in the field of Neuroimaging as applied to Neuroscience. His main research interests are the investigation of neurodegenerative and inflammatory diseases of the CNS, using both structural and functional quantitative MR techniques. He also enthusiastically runs many other projects focusing on various neurological and psychiatric conditions, such as Myotonic Dystrophy and OCD. More recently, he has been focusing on the combination of different techniques, such as MRI and transcranial magnetic stimulation (TMS) or MRI and stimulation of the autonomic nervous system.


Currently, Marco contributes actively to the teaching of neurology and neuroscience to undergraduate and postgraduate students.

Selected publications

Cercignani M, Giulietti G, Dowell NG, Gabel M, Broad R, Leigh PN, Harrison NA, Bozzali M. Characterizing axonal myelination within the healthy population: a tract-by-tract mapping of effects of age and gender on the fiber g-ratio. Neurobiol Aging 2017 Jan;49:109-118. doi: 10.1016/j.neurobiolaging.2016.09.016.

Makovac E, Cercignani M, Serra L, Torso M, Spanò B, Petrucci S, Ricciardi L, Ginevrino M, Caltagirone C, Bentivoglio AR, Valente EM, Bozzali M. Brain Connectivity Changes in Autosomal Recessive Parkinson Disease: A Model for the Sporadic Form. PLoS One. 2016 Oct 27;11(10):e0163980. doi: 10.1371/journal.pone.0163980. 

Serra L, Musicco M, Cercignani M, Torso M, Spanò B, Mastropasqua C, Giulietti G, Marra C, Bruno G, Koch G, Caltagirone C,Bozzali M.Cognitive reserve and the risk for Alzheimer's disease: a longitudinal study. Neurobiol Aging 2015 Feb;36(2):592-600. doi: 10.1016/j.neurobiolaging.2014.10.010.

Serra L, Silvestri G, Petrucci A, Basile B, Masciullo M, Makovac E, Torso M, Spanò B, Mastropasqua C, Harrison NA, Bianchi ML, Giacanelli M, Caltagirone C, Cercignani M, Bozzali M. Abnormal functional brain connectivity and personality traits in myotonic dystrophy type 1. JAMA Neurol 2014 May;71(5):603-11. doi: 10.1001/jamaneurol.2014.130.

Basile B, Mancini F, Macaluso E, Caltagirone C, Bozzali M. Abnormal processing of deontological guilt in obsessive-compulsive disorder. Brain Struct Funct 2014 Jul;219(4):1321-31. doi: 10.1007/s00429-013-0570-2.

Bozzali M, Spanò B, Parker GJ, Giulietti G, Castelli M, Basile B, Rossi S, Serra L, Magnani G, Nocentini U, Caltagirone C, Centonze D, Cercignani M. Anatomical brain connectivity can assess cognitive dysfunction in multiple sclerosis. Mult Scler 2013 Aug;19(9):1161-8. doi: 10.1177/1352458512474088. 

Basile B, Bassi A, Calcagnini G, Strano S, Caltagirone C, Macaluso E, Cortelli P, Bozzali M. Direct stimulation of the autonomic nervous system modulates activity of the brain at rest and when engaged in a cognitive task. Hum Brain Mapp 2013 Jul;34(7):1605-14. doi: 10.1002/hbm.22013. 

Borroni B, Alberici A, Cercignani M, Premi E, Serra L, Cerini C, Cosseddu M, Pettenati C, Turla M, Archetti S, Gasparotti R, Caltagirone C, Padovani A, Bozzali M. Granulin mutation drives brain damage and reorganization from preclinical to symptomatic FTLD. Neurobiol Aging 2012 Oct;33(10):2506-20. doi: 10.1016/j.neurobiolaging.2011.10.031.

Gili T, Cercignani M, Serra L, Perri R, Giove F, Maraviglia B, Caltagirone C, Bozzali M. Regional brain atrophy and functional disconnection across Alzheimer's disease evolution. J Neurol Neurosurg Psychiatry 2011 Jan;82(1):58-66. doi: 10.1136/jnnp.2009.199935.

Koch G, Cercignani M, Bonnì S, Giacobbe V, Bucchi G, Versace V, Caltagirone C, Bozzali M. Asymmetry of parietal interhemispheric connections in humans. J Neurosci 2011 Jun 15;31(24):8967-75. doi: 10.1523/JNEUROSCI.6567-10.2011.