Project description
Previous research has identified that feelings of low self-worth are a central feature of major depressive disorder (MDD) symptoms. Unfortunately, many current treatments for MDD do not address low self-worth specifically, and this might result in patients not responding as well as they could. In this study, we aim to use fMRI neurofeedback with MDD patients to try to change their brain activity towards a healthier pattern. We will use the subgenual cingulate cortex (SCC) as our region-of-interest, a region with well-established links to self-blaming emotions. Participants will also be required to undergo some clinical and psychological assessments before and after the neurofeedback in order to identify any changes in thoughts and feelings.