Skip to main contentSkip to footer
A finger pointing at a scan
Brighton & Sussex Medical School

Our staff

BSMS > About BSMS > Contact us > Staff > Dr Jessica Eccles

Dr Jessica Eccles

Dr Jessica Eccles

Dr Jessica Eccles MB ChB, Dip(French), MA, MSc, MRCPsych, PhD, PGCert HE

Clinical Senior Lecturer and MQ Arthritis Research UK Fellow
Location: Trafford Centre for Medical Research, University of Sussex, Brighton, BN1 9RR

PA: Rosie Mulgrue
T: 01273 876937

Areas of expertise: Brain-Body Interactions, Joint hypermobility, Liaison Psychiatry

Research areas: Neuroscience, Psychiatric manifestations of connective tissue disorders, Mechanisms of chronic pain and fatigue
Other websites: Orcid, Linkedin

Twitter: @bendybrain 
Instagram: @drbendybrain


Jessica Eccles trained in medicine at University of Cambridge and University of Oxford, completing a BA in The History and Philosophy of Science, sparking a keen interest in philosophy of mind and brain-body interactions, and since graduation from medical school has pursued a combined academic clinical path at Brighton and Sussex Medical School. As an MRC Clinical Research Training Fellow she recently completed her PhD in the relationship between joint hypermobility, autonomic dysfunction and psychiatric symptoms and is now an NIHR Academic Clinical Lecturer. She holds honorary clinical contracts with both Sussex Partnership NHS Foundation Trust and Brighton and Sussex University Hospitals NHS Trust.


Dr Eccles is currently working on an Academy of Medical Sciences grant to explore neural connectivity in hypermobility using leading edge Human Connectome Project techniques. To see if you are eligible to take part in this Brighton based study please click here.  

Her Academy of Medical Sciences Webcast on exploring the link between joint hypermobility and anxiety is available here.

She was recently awarded a prestigious MQ Arthritis Research UK Fellows Award to conduct a randomised clinical trial of a new targeted treatment for anxiety in hypermobility

Alongside clinical academic colleagues at BSMS, Professor Neil Harrison (link to his page) and Dr Alessandro Colasanti, Dr Eccles is a clinician in the exciting new Immunopsychiatry Service based at Sussex Partnership NHS Foundation Trust. 

Dr Eccles has been awarded a grant from Dysautonomia International and will be working with Dr Valeria Iodice, Prof Critchley, Prof Cercignani, Dr Nagai, Dr Asslanni, Prof Peter Rowe, Prof Murphy and Dr Giovanni to explore multi-modal correlates of ‘brain fog’ in Postural Tachycardia Syndrome

Dr Eccles is working with Prof Davies, Prof Harrison, Prof Cercignani, Prof Critchley and Dr Tarzi to explore brain-body interactions in Fibromyalgia and ME/CFS. This involves autonomics, inflammatory and cytokine markers, brain imaging and genomics. Read more information as a patient here. Volunteer as a healthy control hereThis research was recently discussed

Read more about the initial findings from Dr Eccles' study in pain and fatigue here >

Watch Dr Eccles' video about her Fibromyalgia research here > 

A video exploring some of the insights from Dr Eccles' work is available here >

Dr Eccles recently recorded a podcast about the relationship between neurodivergency and hypermobility, please listen here >

And Dr Eccles recorded another on hypermobility, fatigue, anxiety and trauma. Listen here >


Jessica delivers a highly popular  SSC entitled ‘Psychiatry and Other Arts’ for Module 202. She has supervised several IRP students and her most recent student won a prize for their work. She has supervised a University of Sussex Junior Research Associate and Wellcome Trust Summer Studentships and lectures and examines on both the undergraduate and postgraduate curriculum.  


Davies, Geoff, Csecs, Jenny L L, Ball, Heather, Dare, Jess, Bremner, Stephen, Hosking, Robin, Critchley, Hugo D, Grey, Nick and Eccles, Jessica A (2021) Altering Dynamics of Autonomic Processing Therapy (ADAPT) trial: a novel, targeted treatment for reducing anxiety in joint hypermobility. Trials, 22 (1). a645 1-10. ISSN 1745-6215

Sharp, Harriet Emma Clare, Critchley, Hugo D and Eccles, Jessica A (2021) Connecting brain and body: transdiagnostic relevance of connective tissue variants to neuropsychiatric symptom expression. World Journal of Psychiatry, 11 (10). pp. 1-15. ISSN 2220-3206

Ahmed J, Eccles J A. Accuracy of depression score: a positive HADS score may only be the tip of the iceberg BMJ 2021; 373 :n1541 doi:10.1136/bmj.n1541

Eccles, Jessica Anne, Ascott, Anna, McGeer, Rona, Hills, Emma, St. Clair Jones, Anja, Page, Lisa A, Smith, Melissa A, Loewenberger, Alana and Gregory, Jemima (2020) Inflammatory bowel disease psychological support pilot reduces inflammatory bowel disease symptoms and improves psychological wellbeing. Frontline Gastroenterology. pp. 1-4. ISSN 2041-4137

Eccles, Jessica, Thompson, Beth, Themelis, Kristy, Amato, Marisa L, Stocks, Robyn, Pound, Amy, Jones, Anna-Marie, Cipinova, Zdenka, Shah-Goodwin, Lorraine, Timeyin, Jean, Thompson, Charlotte R, Batty, Thomas, Harrison, Neil A, Critchley, Hugo D and Davies, Kevin A (2021) Beyond bones: the relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study. Clinical Medicine, 21 (1). pp. 53-58. ISSN 1470-2118

Eccles, Jessica A and Davies, Kevin A (2021) The challenges of chronic pain and fatigue. Clinical Medicine, 21 (1). pp. 19-27. ISSN 1470-2118

Click here to elements profile >