Selected publications
Mitchell, Simon (2021) What will B will B: identifying molecular determinants of diverse B-cell fate decisions through systems biology. Frontiers in Cell and Developmental Biology, 8. a616592 1-8. ISSN 2296-634X
Kennedy, Emma, Coulter, Eve Marie, Halliwell, Emma, Profitos-Peleja, Nuria, Walsby, Elisabeth, Clark, Barnaby, Phillips, Elizabeth H, Burley, Thomas A, Mitchell, Simon, Devereux, Stephen, Jones, Christopher Iain, Johnston, Rosalynd, Chevassut, Timothy J, Pepper, Chris, Pepper, Andrea G S and others, (2021) TLR9 expression in Chronic Lymphocytic Leukemia identifies a pro-migratory subpopulation and novel therapeutic target. Blood. pp. 1-32. ISSN 0006-4971
Oliver Metzig, Marie, Tang, Ying, Mitchell, Simon, Taylor, Brooks, Foreman, Robert, Wollman, Roy and Hoffmann, Alexander (2020) An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions. Molecular Systems Biology, 16 (12). e9677 1-17. ISSN 1744-4292
Latifi, Shahrzad, Mitchell, Simon, Habibey, Rouhollah, Hosseini, Fouzhan, Donzis, Elissa, Estrada-Sánchez, Ana María, Nejad, H Rezaei, Levine, Michael, Golshani, Peyman and Carmichael, S Thomas (2020) Neuronal network topology indicates distinct recovery processes after stroke. Cerebral Cortex. ISSN 1047-3211
Ngo, Kim A, Kishimoto, Kensei, Davis-Turak, Jeremy, Pimplaskar, Aditya Pimplaskar, Cheng, Zhang, Spreafico, Roberto, Chen, Emily Y, Tam, Amy, Ghosh, Gourisankar, Mitchell, Simon and Hoffman, Alexander (2020) Dissecting the regulatory strategies of NF-kB RelA target genes in the inflammatory response reveals differential transactivation logics. Cell reports, 30 (8). pp. 2758-2775. ISSN 2211-1247
Roy, Koushik, Mitchell, Simon, Liu, Yi, Ohta, Sho, Lin, Yu-sheng, Metzig, Marie Oliver, Nutt, Stephen L. and Hoffmann, Alexander (2019) A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation. Immunity, 50 (3). 616-628.e6. ISSN 1074-7613
Mitchell, Simon, Mercado, Ellen L, Adelaja, Adewunmi, Ho, Jessica Q, Cheng, Quen J, Ghosh, Gourisankar and Hoffmann, Alexander (2019) An NFkB activity calculator to delineate signaling crosstalk: type I and II interferons enhance NFkB via distinct mechanisms. Frontiers in Immunology, 10 (1425). pp. 1-16. ISSN 1664-3224
Mitchell, Simon and Hoffmann, Alexander (2019) Substrate complex competition – a regulatory motif that allows NFkB RelA to license but not amplify NFkB RelB. Proceedings of the National Academy of Sciences, 116 (21). pp. 10592-10597. ISSN 1091-6490
Yeom, Kyu-Hyeon, Mitchell, Simon, Linares, Anthony J, Zheng, Sika, Lin, Chia-Ho, Wang, Xiao-Jun, Hoffmann, Alexander and Black, Douglas L (2018) Polypyrimidine tract-binding protein blocks miRNA-124 biogenesis to enforce its neuronal-specific expression in the mouse. Proceedings of the National Academy of Sciences, 115 (47). E11061-E11070. ISSN 0027-8424
Mitchell, Simon and Hoffmann, Alexander (2018) Identifying noise sources governing cell-to-cell variability. Current Opinion in Systems Biology, 8. pp. 39-45. ISSN 2452-3100
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