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BSMS > About BSMS > Contact us > Staff > Dr Yoko Nagai

Dr Yoko Nagai

Dr Yoko Nagai

Dr Yoko Nagai (BSc, PhD, MBA, PGDip Law)

Senior Lecturer in Translational Neuroscience
T: +44 (0)1273 876828
Location: Trafford Centre for Medical Research, BSMS, University of Sussex, BN1 9RY

Areas of expertise: Clinical Neuroscience and Applied psychology, Brain-Body interaction, Biofeedback

Research areas: Role of autonomic function in epilepsy, Biofeedback treatment on neurological and psychiatric conditions, Intellectual Property law and Human Rights law, Quadruple Helix Model

Other relevant positions: Academic Tutor (Year 1&2), Individual Research Project supervisor (Year 4)

Other website: - Therapy for Drug-Resistant Epilepsy: Online biofeedback therapy for epilepsy based on cutting-edge neuroscientific research.



Dr Yoko Nagai is a translational neuroscientist with interests in mind-body interaction and human consciousness. Her main work involves the investigation and development of a non-drug therapy for patients with drug-resistant epilepsy. The therapy is termed as Autonomic Cognitive Rehabituation training (ACRT). This pioneering work attracted funding for clinical trials from various grant bodies (Bial Foundation, Tourette Syndrome Association USA, Wellcome Trust). More recently, her research interests expanded from human wellbeing to social wellbeing, integrating her educations in science, business and law. She is a member of International League Against Epilepsy (ILAE: UK), American Epilepsy Society and Inns of Court. 


Dr Nagai's EPILEPSY TREATMENT on BBC South East Today

Selected publications

Nagai Y. Modulation of autonomic activity in neurological conditions: epilepsy and Tourette Syndrome. Frontiers Autonomic Neuroscience. 2015, volume9, article 278

Nagai Y and Trimble MR. Long-term effects of electrodermal biofeedback training on seizure control in patients with drug-resistant epilepsy: Two case reports. Epilepsy Research, 2014, 108: 149-52.

Nagai Y, Cavanna AE, Critchley HD, Stern JS, Robertson MM, Joyce EM. Biofeedback treatment for Tourette Syndrome: Preliminary randomized controlled trial. Cogn Behav Neurol. 2014, 27:17-24.

Nagai Y and Trimble MR, Biofeedback treatment and seizure control. In Mostfsky D (Ed), Hand book of Behavioural Medichine. Wiley-Blackwell, 2014, 149-152.

Nagai Y. Biofeedback and epilepsy. Curr Neurol Neurosci Rep, 2011, 11, 433-450.

Nagai Y, Critchley HD, Rothwell JC, Duncan JS, Trimble MR. Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy. Psychosomatic Medicine 2009, 71: 84-92.

Nagai Y, Goldstein LH, Fenwick PBC, Trimble MR.  Clinical efficacy of biofeedback treatment on reducing seizures in adult epilepsy: a preliminary randomized controlled study. Epilepsy & Behaviour 2004, Vol 5/2: 216-223.

Nagai Y, Critchley HD, Featherstone E, Fenwick PBC, Trimble MR, Dolan RJ. Brain activity relating to the Contingent Negative Variation (CNV): fMRI investigation. Neuroimage 2004, 21:1232-1241.

Nagai Y, Critchley HD, Featherstone E, Trimble MR, Dolan RJ. Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level (SCL): a physiological account of a “default mode” of brain function. Neuroimage 2004, 22:243-251.

Nagai Y, Goldstein LH, Critchley HD, Fenwick PBC. Influence of sympathetic autonomic arousal on contingent negative variation: implications for a therapeutic behavioural intervention in epilepsy. Epilepsy Res 2004, 58:185-193.

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