Skip to main contentSkip to footer
finger pointing scan
Brighton & Sussex Medical School

staff profiles

BSMS > About BSMS > Contact us > Staff > Professor Martin Llewelyn

Professor Martin Llewelyn

AMR Researchers - Dr Martin Llewelyn

Professor Martin Llewelyn (BSc, FRCP, DTMH, PhD)

Professor in Infectious Diseases
E: M.J.Llewelyn@bsms.ac.uk
T: +44 (0)1273 876671
Location: Medical Research Building, Room 1.08, BSMS, University of Sussex, BN1 9PS

DA: Sandy E Gray
+44(0)1273 877017
s.gray@bsms.ac.uk

Areas of expertise: Healthcare associated infection; antimicrobial resistance
Research areas: Infection and immunology

Biography

Prof Martin Llewelyn has worked at BSMS since 2004 and holds an honorary contract at Brighton and Sussex University Hospitals NHS Trust as a Consultant in Infectious Diseases. He did his Undergraduate medical training at the Royal London Hospital graduating in 1992. After Medical House-Officer and Senior House Officer posts in North East London he undertook higher specialist training in Infectious Diseases and General Internal Medicine in North Thames. He spent three years on an MRC-funded research training fellowship at Imperial College studying host immune responses to bacterial superantigen toxins. He obtained his CCT and PhD in 2004. 

Research

Martin’s research is focused on the common, life-threatening infections which affect patients in the NHS, in particular on healthcare associated and antibiotic resistant pathogens such as Staphylococcus aureus and Clostridium difficile. Major current themes of his research are application of microbial genome sequencing to the study of transmission and pathogenesis of S. aureus infection and reducing antibiotic usage in hospital through optimising treatment strategies. Martin’s research is undertaken in collaboration with groups such as Modernising Medical Microbiology, the International Staphylococcus Aureus Collaboration and the NIHR-funded Antibiotic Reduction and Conservation in Hospitals (ARK-Hospital) programme.

Teaching

Martin teaches extensively on the Undergraduate Course at BSMS in Clinical Infectious Diseases, Microbiology and Immunology. In the first term of Year 1 ‘Foundations of Health and Disease’ he teaches basic microbiology and about the role of the host and pathogen in the outcome of infection. In Year 3 he teaches about the scientific basis of infectious diseases and the immune response to infection. In the Fourth Year specialist rotation in infectious diseases he teaches the diagnosis and management of common infectious diseases. Each year Martin supervises medical students undertaking both clinical and laboratory based individual research projects.

Selected publications

Gordon, N C, Pichon, B, Golubchik, T, Wilson, D J, Paul, J, Blanc, D S, Cole, K, Collins, J, Cortes, N, Cubbon, M, Gould, F K, Jenks, P J, Llewelyn, M, Nash, J Q, Orendi, J M, Paranthaman, K, Price, J, Senn, L, Thomas, H L, Wyllie, S, Crook, D W, Peto, T E A, Walker, A S and Kearns, A M (2017) Whole genome sequencing reveals the contribution of long-term carriers in Staphylococcus aureus outbreak investigation. Journal of Clinical Microbiology. ISSN 0095-1137.

Behar, Laura, Chadwick, David, Dunne, Angela, Jones, Christopher I, Procter, Clare, Rajkumar, Chakravarthi, Sharratt, Paula, Stanley, Philip, Whiley, Angela, Wilks, Mark and Llewelyn, Martin J (2017) Toxigenic Clostridium difficile colonization among hospitalised adults; risk factors and impact on survival. Journal of Infection. ISSN 01634453.

Ledda, Alice, Price, James R, Cole, Kevin, Llewelyn, Martin J, Kearns, Angela M, Crook, Derrick W, Paul, John and Didelot, Xavier (2017) Re-emergence of methicillin susceptibility in a resistant lineage of Staphylococcus aureus. Journal of Antimicrobial Chemotherapy. dkw570. ISSN 0305-7453.

Price, James R, Cole, Kevin, Bexley, Andrew, Kostiou, Vasiliki, Eyre, David W, Golubchik, Tanya, Wilson, Daniel J, Crook, Derrick W, Walker, A Sarah, Peto, Timothy E A, Llewelyn, Martin J and Paul, John (2017) Transmission of Staphylococcus aureus between health-care workers, the environment, and patients in an intensive care unit: a longitudinal cohort study based on whole-genome sequencing. Lancet Infectious Diseases, 17 (2). pp. 207-214. ISSN 1473-3099.

Earle, Sarah G, Wu, Chieh-Hsi, Charlesworth, Jane, Stoesser, Nicole, Gordon, N. Claire, Walker, Timothy M, Spencer, Chris C A, Iqbal, Zamin, Clifton, David A, Hopkins, Katie L, Woodford, Neil, Smith, E Grace, Ismail, Nazir, Llewelyn, Martin J, Peto, Tim E, Crook, Derrick W, McVean, Gil, Walker, A Sarah and Wilson, Daniel J (2016) Identifying lineage effects when controlling for population structure improves power in bacterial association studies. Nature Microbiology, 1. p. 16041. ISSN 2058-5276.

Harris, P N A, McNamara, J F, Lye, D C, Davis, J S, Bernard, L, Cheng, A C, Doi, Y, Fowler, V G, Kaye, K S, Leibovici, L, Lipman, M J, Llewelyn, M J, Munoz-Price, S, Paul, M, Peleg, A Y, Rodríguez-Baño, J, Rogers, B A, Seifert, H, Thamlikitkul, V, Thwaites, G, Tong, S Y C, Turnidge, J, Utili, R, Webb, S A R and Paterson, D L (2016) Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition. Clinical Microbiology and Infection. ISSN 1198-743X.

Caserta, Stefano, Kern, Florian, Cohen, Jonathan, Drage, Stephen, Newbury, Sarah F and Llewelyn, Martin J (2016) Circulating plasma microRNAs can differentiate human sepsis and Systemic Inflammatory Response Syndrome (SIRS). Scientific Reports, 6. p. 28006. ISSN 2045-2322.

Fitzpatrick, J M, Biswas, J S, Edgeworth, J D, Islam, J, Jenkins, N, Judge, R, Lavery, A J, Melzer, M, Morris-Jones, S, Nsutebu, E F, Peters, J, Pillay, D G, Pink, F, Price, J R, Scarborough, M, Thwaites, G E, Tilley, R, Walker, A S and Llewelyn, M J (2015) Gram-negative bacteraemia; a multi-centre prospective evaluation of empiric antibiotic therapy and outcome in English acute hospitals. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 22 (3). pp. 244-251. ISSN 1469-0691.