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BSMS > About BSMS > Contact us > Staff > Professor Pietro Ghezzi

Professor Pietro Ghezzi

Prof Pietro Ghezzi

Professor Pietro Ghezzi (PhD)

Postgraduate Tutor and Emeritus Professor

Areas of expertise: Inflammatory cytokines and the mechanisms of innate immunity; redox regulation of immunity; analysis of quality of health information

Research areas: Infection and immunology; neuroscience; information quality


Professor Pietro Ghezzi has a PhD in Pharmacology from the Mario Negri Institute in Milano and a Post-graduate Certificate in Higher Education at the University of Sussex.

From 1991 to 2008 he was the Head of the Laboratory of Neuroimmunology, Istituto Mario Negri, Milano and from 1998 to 2000 he was Research Associate at Stanford University School of Medicine, in the laboratory of the late Len Herzenberg. He joined BSMS in 2008.

Selected publications

Gyetvai G, Hughes T, Wedmore F, Roe C, Heikal L, Ghezzi P, Mengozzi M. Erythropoietin IncreasesMyelination in Oligodendrocytes: Gene Expression Profiling Reveals Early Induction of Genes Involvedin Lipid Transport and Metabolism. Front Immunol. 2017;8:1394.

Diotallevi M, Checconi P, Palamara AT, Celestino I, Coppo L, Holmgren A, Abbas K, Peyrot F, MengozziM, Ghezzi P. Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in aMacrophage Cell Line Independently of Its Antioxidant Properties. Front Immunol. 2017;8:1239.

Aslam R, Gibbons D, Ghezzi P. Online Information on Antioxidants: Information Quality Indicators,Commercial Interests, and Ranking by Google. Front Public Health. 2017;5:90.

Ghezzi P, Jaquet V, Marcucci F, Schmidt HHHW. The oxidative stress theory of disease: levels ofevidence and epistemological aspects. Br J Pharmacol. 2017;174(12):1784-1796.

Mullen L, Seavill M, Hammouz R, Bottazzi B, Chan P, Vaudry D, Ghezzi P. Development of 'RedoxArrays' for identifying novel glutathionylated proteins in the secretome. Sci Rep. 2015;5:14630.

Maki A, Evans R, Ghezzi P. Bad News: Analysis of the Quality of Information on Influenza PreventionReturned by Google in English and Italian. Front Immunol. 2015;6:616.

Checconi P, Salzano S, Bowler L, Mullen L, Mengozzi M, Hanschmann EM, Lillig CH, Sgarbanti R,Panella S, Nencioni L, Palamara AT, Ghezzi P. Redox proteomics of the inflammatory secretomeidentifies a common set of redoxins and other glutathionylated proteins released in inflammation,influenza virus infection and oxidative stress. PLoS One. 2015;10(5):e0127086.

Mullen L, Hanschmann EM, Lillig CH, Herzenberg LA, Ghezzi P. Cysteine Oxidation TargetsPeroxiredoxins 1 and 2 for Exosomal Release through a Novel Mechanism of Redox-Dependent Secretion.Mol Med. 2015;21:98-108.

Salzano S, Checconi P, Hanschmann EM, Lillig CH, Bowler LD, Chan P, Vaudry D, Mengozzi M, Coppo L,Sacre S, Atkuri KR, Sahaf B, Herzenberg LA, Herzenberg LA,Mullen L, Ghezzi P. Linkage ofinflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as adanger signal. Proc Natl Acad Sci U S A. 2014;111(33):12157-62.

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