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Dr Tabea Fullstone

A head and shoulders photo of BSMS researcher Tabea Fullstone

Dr Tabea Fullstone

Research Fellow Cancer Systems Biology
E: T.Fullstone@bsms.ac.uk

Areas of interest: Cancer cell biology; Systems biology; Epigenetics (incl. genome methylation and epigenomics); Ordinary differential equations, difference equations and dynamical systems; Biochemistry and cell biology; Signal transduction

BACKGROUND IMAGE FOR PANEL

Biography

Tabea completed her BSc and MSc in Technical Biology at the University of Stuttgart, where she focused on tumour biology and computational approaches, culminating in a systems biology thesis on ODE modelling of apoptosis. During her PhD in Cancer Epigenetics at the University of Stuttgart, she combined experimental techniques with large-scale data analysis to study epigenetic plasticity in cellular stress responses.

She joined the Brighton and Sussex Medical School in 2026 as a Research Fellow in Laboratory and Computational Systems Biology in Cancer Research. In this role she will be applying computational, data-driven and experimental approaches to advance lymphoma research by exploring ways to better guide treatment decisions and understand patient responses.

Selected publications

Fullstone TL, Fischer LFJ, Bohmeier M, Frings-Meuthen P, Crucian BE, Rathert P. Epigenomic profiling of immune cell subtypes reveals H3K27ac-marked stress signatures after long-duration spaceflight. Sci Rep. 2025 Sep 12;15(1):32445. doi: 10.1038/s41598-025-17930-1. PMID: 40940371; PMCID: PMC12432228.

Fullstone TL, Rohm H, Kaltofen T, Hierlmayer S, Reichenbach J, Schweikert S, Knodel F, Loeffler AK, Mayr D, Jeschke U, Mahner S, Kessler M, Trillsch F, Rathert P. Identification of FLYWCH1 as a regulator of platinum-resistance in epithelial ovarian cancer. NAR Cancer. 2025 Apr 4;7(2):zcaf012. doi: 10.1093/narcan/zcaf012. PMID: 40191655; PMCID: PMC11970373.

Bauer TL, Collmar K, Kaltofen T, Loeffler AK, Decker L, Mueller J, Pinter S, Eisler SA, Mahner S, Fraungruber P, Kommoss S, Staebler A, Francis L, Conlan RS, Zuber J, Jeschke U, Trillsch F, Rathert P. Functional Analysis of Non-Genetic Resistance to Platinum in Epithelial Ovarian Cancer Reveals a Role for the MBD3-NuRD Complex in Resistance Development. Cancers (Basel). 2021 Jul 28;13(15):3801. doi: 10.3390/cancers13153801. PMID: 34359703; PMCID: PMC8345099.

Fullstone G, Bauer TL, Guttà C, Salvucci M, Prehn JHM, Rehm M. The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer. Cell Death Differ. 2020 Oct;27(10):2828-2842. doi: 10.1038/s41418-020-0545-9. Epub 2020 Apr 27. PMID: 32341447; PMCID: PMC7493894.

Bauer TL, Buchholz PCF, Pleiss J. The modular structure of α/β-hydrolases. FEBS J. 2020 Mar;287(5):1035-1053. doi: 10.1111/febs.15071. Epub 2019 Oct 10. PMID: 31545554.