What we explore
Cognitive Ageing
Investigating the changes in cognitive abilities that occur with age and identifying the biological, psychological, and social factors contributing to cognitive decline. Examining social, economic, and cultural elements that account for cognitive health disparities in the ageing population. This extends to laboratory studies exploring the impact of psychosocial factors on cognitive, cardiovascular, neuroendocrine, and immune functions. Prospective associations between acute physiological responses to emotional stress and the development of cardiometabolic diseases, stroke, cognitive impairment and dementia are also examined.
Dementia Epidemiology and Factors
Examining population-based studies on dementia and other age-related conditions, with a focus on both non-modifiable factors (e.g., genetics) and modifiable factors (e.g., environmental and social influences). Exploring the biological processes through which social status and psychosocial factors impact the risk of dementia. Our research delves into the intricate interplay between psychological processes, neuroendocrine activation, inflammation, depression and dementia risk.
Psychosocial Resilience and Interventions
Developing strategies to promote healthy cognitive ageing and enhance cognitive and psychosocial resilience. A particular emphasis is placed on understanding the impact of mental stress on inflammatory, metabolic, and haemostatic processes. We investigate the connections between physiological responses and psychosocial risk factors, including low socioeconomic position, depression, and loneliness. In addition, our research aims to explore the role of technology in promoting cognitive health among older adults, involving the development of lifestyle and cognitive interventions to prevent or delay the onset of dementia and evaluating the utility of technology in this context.